Guido Serini
Professor
- Department of Oncology
- SSD: BIO/12 - clinical biochemistry and molecular biology
- ORCID: orcid.org/0000-0002-3502-8367
Contacts
- 0119933508
- 0119933524
- Call gserini
- guido.serini@unito.it
- c/o Istituto di Candiolo, I.R.C.C.S.
Strada Provinciale, 142 km 3,95 - 10060 Candiolo (TO) - https://phd-csqb.campusnet.unito.it/persone/guido.serini
- Contacts VCard
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- Department of Oncology
- Dipartimento di Oncologia
- Artificial Intelligence for Biomedicine and Healthcare
- Laurea Magistrale in Medicina e Chirurgia - sede di Torino
- Laurea magistrale in Medicina e Chirurgia San Luigi Gonzaga
- MedInTO Medicine and Surgery
- Programma MD-PhD della Scuola di Medicina
- Dottorato in Sistemi Complessi per le Scienze della Vita (fino al ciclo 35) - PhD Programme in Complex Systems for Life Sciences (until 35th cycle)
- PhD in Complex Systems for Quantitative Biomedicine
- PhD Programme in Complex Systems for Life Sciences (until 35th cycle)
Curriculum vitae
Research products
All my research productsSelected research products
Gioelli N, Neilson LJ, Wei N, Villari G, Chen W, Kuhle B, Ehling M, Maione F, Willox S, Brundu S, Avanzato D, Koulouras G, Mazzone M, Giraudo E, Yang XL, Valdembri D, Zanivan S, Serini G. (2022) Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability. Nature Communications 13(1) 4188 [DOI PMID]
Camillo C, Facchinello N, Villari G, Mana G, Gioelli N, Sandri C, Astone M, Tortarolo D, Clapero F, Gays D, Oberkersch RE, Arese M, Tamagnone L, Valdembri D, Santoro MM, Serini G. (2021) LPHN2 inhibits vascular permeability by differential control of endothelial cell adhesion. The Journal of cell biology 220(11):e202006033 [DOI PMID]
Gioelli N, Maione F, Camillo C, Ghitti M, Valdembri D, Morello N, Darche M, Zentilin L, Cagnoni G, Qiu Y, Giacca M, Giustetto M, Paques M, Cascone I, Musco G, Tamagnone L, Giraudo E, Serini G. (2018) A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent. Science Translational Medicine 10(442) [DOI PMID]
Regano D, Visintin A, Clapero F, Bussolino F, Valdembri D, Maione F, Serini G*, Giraudo E*. (2017) Sema3F (Semaphorin 3F) Selectively Drives an Extraembryonic Proangiogenic Program. Arteriosclerosis, Thrombosis, and Vascular Biology 37(9) 1710-1721 [DOI PMID] *Co-corresponding authors
Serini G, Bussolino F, Maione F, Giraudo E. (2013) Class 3 semaphorins: physiological vascular normalizing agents for anti-cancer therapy. Journal of Internal Medicine 273(2) 138-55 [DOI PMID] Review
Maione F, Molla F, Meda C, Latini R, Zentilin L, Giacca M, Seano G, Serini G*, Bussolino F*, Giraudo E*. (2009) Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models. The Journal of Clinical Investigation 119(11) 3356-72 [DOI PMID] *Shared senior authorship
Courses
- Biochemistry, cellular and molecular biology (ONC0251)
Artificial Intelligence for Biomedicine and Healthcare - Biochimica (Canale C) (SME0980)
Laurea Magistrale in Medicina e Chirurgia - sede di Torino - Biochimica clinica (canale C) (MED0175A)
Laurea Magistrale in Medicina e Chirurgia - sede di Torino - Biochimica clinica (canale D) (MED0175A)
Laurea Magistrale in Medicina e Chirurgia - sede di Torino - Biochimica metabolica (canale C) (SME0980B)
Laurea Magistrale in Medicina e Chirurgia - sede di Torino - Cell Biology and Physiopatholology
PhD Programme in Complex Systems for Life Sciences (until 35th cycle) - Cell Biology and Physiopatholology
Dottorato in Sistemi Complessi per le Scienze della Vita (fino al ciclo 35) - PhD Programme in Complex Systems for Life Sciences (until 35th cycle) - Laboratory Medicine (SCB0226)
MedInTO Medicine and Surgery - Laboratory Medicine - module of Clinical Biochemistry and Molecular Biology (SCB0226A)
MedInTO Medicine and Surgery - Medicina di Laboratorio - Modulo di Biochimica clinica (MSL0427A)
Laurea magistrale in Medicina e Chirurgia San Luigi Gonzaga - Medicina di Laboratorio (canale C) (MED0175)
Laurea Magistrale in Medicina e Chirurgia - sede di Torino - Medicina di Laboratorio (canale D) (MED0175)
Laurea Magistrale in Medicina e Chirurgia - sede di Torino - ONC0251E Clinical biochemistry and molecular biology (ONC0251E)
Artificial Intelligence for Biomedicine and Healthcare - Ruolo del controllo dell’adesione cellulare nella 'normalizzazione' dei vasi sanguigni tumorali. Responsabile prof Guido Serini
Programma MD-PhD della Scuola di Medicina
Research topics
Characterization of therapeutically actionable molecular mechanisms that regulate vascular endothelial cell adhesion during physiological and tumor angiogenesis.
Activities in agenda
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