PhD in Complex Systems for Quantitative Biomedicine

Research products

All my research products

Selected research products

Gioelli N, Neilson LJ, Wei N, Villari G, Chen W, Kuhle B, Ehling M, Maione F, Willox S, Brundu S, Avanzato D, Koulouras G, Mazzone M, Giraudo E, Yang XL, Valdembri D, Zanivan S, Serini G. (2022) Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability. Nature Communications 13(1) 4188 [DOI  PMID]

Camillo C, Facchinello N, Villari G, Mana G, Gioelli N, Sandri C, Astone M, Tortarolo D, Clapero F, Gays D, Oberkersch RE, Arese M, Tamagnone L, Valdembri D, Santoro MM, Serini G. (2021) LPHN2 inhibits vascular permeability by differential control of endothelial cell adhesion. The Journal of cell biology 220(11):e202006033 [DOI  PMID]

Gioelli N, Maione F, Camillo C, Ghitti M, Valdembri D, Morello N, Darche M, Zentilin L, Cagnoni G, Qiu Y, Giacca M, Giustetto M, Paques M, Cascone I, Musco G, Tamagnone L, Giraudo E, Serini G. (2018) A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent. Science Translational Medicine 10(442) [DOI  PMID]

Regano D, Visintin A, Clapero F, Bussolino F, Valdembri D, Maione F, Serini G*, Giraudo E*. (2017) Sema3F (Semaphorin 3F) Selectively Drives an Extraembryonic Proangiogenic Program. Arteriosclerosis, Thrombosis, and Vascular Biology 37(9) 1710-1721 [DOI  PMID] *Co-corresponding authors

Serini G, Bussolino F, Maione F, Giraudo E. (2013) Class 3 semaphorins: physiological vascular normalizing agents for anti-cancer therapy. Journal of Internal Medicine 273(2) 138-55 [DOI  PMID] Review

Maione F, Molla F, Meda C, Latini R, Zentilin L, Giacca M, Seano G, Serini G*, Bussolino F*, Giraudo E*. (2009) Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models. The Journal of Clinical Investigation 119(11) 3356-72 [DOI  PMID] *Shared senior authorship

 

Courses

• Biochemistry, cellular and molecular biology (ONC0251)
  Artificial Intelligence for Biomedicine and Healthcare
• Biochimica (Canale C) (SME0980)
  Laurea Magistrale in Medicina e Chirurgia - sede di Torino
• Biochimica clinica (canale C) (MED0175A)
  Laurea Magistrale in Medicina e Chirurgia - sede di Torino
• Biochimica clinica (canale D) (MED0175A)
  Laurea Magistrale in Medicina e Chirurgia - sede di Torino
• Biochimica metabolica (canale C) (SME0980B)
  Laurea Magistrale in Medicina e Chirurgia - sede di Torino
• Cell Biology and Physiopatholology
  PhD Programme in Complex Systems for Life Sciences (until 35th cycle)
• Cell Biology and Physiopatholology
  Dottorato in Sistemi Complessi per le Scienze della Vita (fino al ciclo 35) - PhD Programme in Complex Systems for Life Sciences (until 35th cycle)
• Laboratory Medicine (SCB0226)
  MedInTO Medicine and Surgery
• Laboratory Medicine - module of Clinical Biochemistry and Molecular Biology (SCB0226A)
  MedInTO Medicine and Surgery
• Medicina di Laboratorio - Modulo di Biochimica clinica (MSL0427A)
  Laurea magistrale in Medicina e Chirurgia San Luigi Gonzaga
• Medicina di Laboratorio (canale C) (MED0175)
  Laurea Magistrale in Medicina e Chirurgia - sede di Torino
• Medicina di Laboratorio (canale D) (MED0175)
  Laurea Magistrale in Medicina e Chirurgia - sede di Torino
• ONC0251E Clinical biochemistry and molecular biology (ONC0251E)
  Artificial Intelligence for Biomedicine and Healthcare
• Ruolo del controllo dell’adesione cellulare nella 'normalizzazione' dei vasi sanguigni tumorali. Responsabile prof Guido Serini
  Programma MD-PhD della Scuola di Medicina

Research topics

Characterization of therapeutically actionable molecular mechanisms that regulate vascular endothelial cell adhesion during physiological and tumor angiogenesis.

Academic bodies

• Department Council - Department of Oncology

• Consiglio di Dipartimento - Dipartimento di Oncologia

Office hours

Contattare personalmente il docente via e-mail o telefonicamente.

Faculty