PhD in Complex Systems for Quantitative Biomedicine

Selected research products

Woo, Xing Yi, Giordano, Jessica, Srivastava, Anuj, Zhao, Zi-Ming, Lloyd, Michael W , de Bruijn, Roebi, Suh, Yun-Suhk, Patidar, Rajesh, Chen, Li, Scherer, Sandra, Bailey, Matthew H , Yang, Chieh-Hsiang, Cortes-Sanchez, Emilio, Xi, Yuanxin, Wang, Jing, Wickramasinghe, Jayamanna, Kossenkov, Andrew V , Rebecca, Vito W , Sun, Hua, Mashl, R Jay, Davies, Sherri R , Jeon, Ryan, Frech, Christian, Randjelovic, Jelena, Rosains, Jacqueline, Galimi, Francesco, Bertotti, Andrea, Lafferty, Adam, O’Farrell, Alice C , Modave, Elodie, Lambrechts, Diether, ter Brugge, Petra, Serra, Violeta, Marangoni, Elisabetta, El Botty, Rania, Kim, Hyunsoo, Kim, Jong-Il, Yang, Han-Kwang, Lee, Charles, Dean, Dennis A , Davis-Dusenbery, Brandi, Evrard, Yvonne A , Doroshow, James H , Welm, Alana L , Welm, Bryan E , Lewis, Michael T , Fang, Bingliang, Roth, Jack A , Meric-Bernstam, Funda, Herlyn, Meenhard, Davies, Michael A , Ding, Li, Li, Shunqiang, Govindan, Ramaswamy, Isella, Claudio, Moscow, Jeffrey A , Trusolino, Livio, Byrne, Annette T , Jonkers, Jos, Bult, Carol J , Medico, Enzo, Chuang, Jeffrey H , Giordano, Silvia, Corso, Simona, (2021)
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.
https://iris.unito.it/handle/2318/1768036

Rosano S , Cora D , Parab S , Zaffuto S , Isella C , Porporato R , Hoza R M , Calogero R A , Riganti C , Bussolino F , Noghero A (2020)
A regulatory microRNA network controls endothelial cell phenotypic switch during sprouting angiogenesis.
https://iris.unito.it/handle/2318/1726233

Isella, Claudio, Vaira, Marco, Robella, Manuela, Bellomo, Sara Erika, Picco, Gabriele, Borsano, Alice, Mignone, Andrea, Petti, Consalvo, Porporato, Roberta, Ulla, Alexandra Ambra, Pisacane, Alberto, Sapino, Anna, Simone, Michele De, Medico, Enzo (2020)
Improved Outcome Prediction for Appendiceal Pseudomyxoma Peritonei by Integration of Cancer Cell and Stromal Transcriptional Profiles.
https://iris.unito.it/handle/2318/1766965

Cascianelli S , Molineris I , Isella C , Masseroli M , Medico E (2020)
Machine learning for RNA sequencing-based intrinsic subtyping of breast cancer.
https://iris.unito.it/handle/2318/1764938

Lupo, Barbara, Sassi, Francesco, Pinnelli, Marika, Galimi, Francesco, Zanella, Eugenia R , Vurchio, Valentina, Migliardi, Giorgia, Gagliardi, Paolo Armando, Puliafito, Alberto, Manganaro, Daria, Luraghi, Paolo, Kragh, Michael, Pedersen, Mikkel W , Horak, Ivan D , Boccaccio, Carla, Medico, Enzo, Primo, Luca, Nichol, Daniel, Spiteri, Inmaculada, Heide, Timon, Vatsiou, Alexandra, Graham, Trevor A , Élez, Elena, Argiles, Guillem, Nuciforo, Paolo, Sottoriva, Andrea, Dienstmann, Rodrigo, Pasini, Diego, Grassi, Elena, Isella, Claudio, Bertotti, Andrea, Trusolino, Livio (2020)
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype.
https://iris.unito.it/handle/2318/1750197

Orzan F , Pagani F , Cominelli M , Triggiani L , Calza S , De Bacco F , Medicina D , Balzarini P , Panciani P P , Liserre R , Buglione M , Fontanella M M , Medico E , Galli R , Isella C , Boccaccio C , Poliani P L (2020)
A simplified integrated molecular and immunohistochemistry-based algorithm allows high accuracy prediction of glioblastoma transcriptional subtypes.
https://iris.unito.it/handle/2318/1766963

Invrea F , Rovito R , Torchiaro E , Petti C , Isella C , Medico E (2020)
Patient-derived xenografts (PDXs) as model systems for human cancer.
https://iris.unito.it/handle/2318/1732700

Chiabotto G , Grignani G , Todorovic M , Martin V , Centomo M L , Prola E , Giordano G , Merlini A , Miglio U , Berrino E , Napione L , Isella C , Capozzi F , Basirico M , Marsero C , Gerardi I , Venesio T , Sangiolo D , Aglietta M , D', ambrosio L , Pignochino Y (2020)
Pazopanib and trametinib as a synergistic strategy against osteosarcoma: Preclinical activity and molecular insights.
https://iris.unito.it/handle/2318/1744216

Corti G , Bartolini A , Crisafulli G , Novara L , Rospo G , Montone M , Negrino C , Mussolin B , Buscarino M , Isella C , Barault L , Siravegna G , Siena S , Marsoni S , Di Nicolantonio F , Medico E , Bardelli A (2019)
A Genomic Analysis Workflow for Colorectal Cancer Precision Oncology.
https://iris.unito.it/handle/2318/1709252

Gurrapu S , Franzolin G , Fard D , Accardo M , Medico E , Sarotto I , Sapino A , Isella C , Tamagnone L (2019)
Reverse signaling by semaphorin 4C elicits SMAD1/5- And ID1/3-dependent invasive reprogramming in cancer cells.
https://iris.unito.it/handle/2318/1716742

Zabarino Antonella Moira, , , Benedetto Claudio, , , Baima Gabriele, , , Santoro Gabriele, (2019)
TOWARDS HUMAN-CENTERED SOCIETY: THE ROLE OF EMOTIONS IN THE COMPANY.
https://iris.unito.it/handle/2318/1713051

Baima Gabriele, , , Santoro Gabriele, , , Ferraris Alberto, (2019)
ENHANCING THE CULTURE AND CREATING VALUE FOR THE TERRITORY THROUGH OPEN INNOVATION: A CASE STUDY.
https://iris.unito.it/handle/2318/1713046

Paolo Biancone, Silvana Secinaro, Valerio Brescia, Davide Calandra (2019)
The Medical Record and the Cycle of Innovation in the Clinical Pathway of Patients Suffering from Pathological Addictions.
https://iris.unito.it/handle/2318/1704103

Md Hakim Ali, Saiful Azhar Rosly, Maha Radwan, Silvana Secinaro (2019)
An Examination of Factors Affecting Excess Liquidity, Evidence from Islamic Banks in Malaysia.
https://iris.unito.it/handle/2318/1702240

Arena, Sabrina, Corti, Giorgio, Durinikova, Erika, Montone, Monica, Reilly, Nicole M, Russo, Mariangela, Lorenzato, Annalisa, Arcella, Pamela, Lazzari, Luca, Rospo, Giuseppe, Pagani, Massimiliano, Cancelliere, Carlotta, Negrino, Carola, Isella, Claudio, Bartolini, Alice, Cassingena, Andrea, Amatu, Alessio, Mauri, Gianluca, Sartore-Bianchi, Andrea, Mittica, Gloria, Medico, Enzo, Marsoni, Silvia, Linnebacher, Michael, Abrignani, Sergio, Siena, Salvatore, Di Nicolantonio, Federica, Bardelli, Alberto (2019)
A Subset of Colorectal Cancers with Cross-Sensitivity to Olaparib and Oxaliplatin.
https://iris.unito.it/handle/2318/1728652

Lazzari L , Corti G , Picco G , Isella C , Montone M , Arcela P , Durinikova E , Zanella E R , Novara L , Barbosa F , Cassingena A , Cancelliere C , Medico E , Sartore-Bianchi A , Siena S , Garnett M J , Bertotti A , Trusolino L , Di Nicolantonio F , Linnebacher M , Bardelli A , Arena S (2019)
Patient-derived xenografts and matched cell lines identify pharmacogenomic vulnerabilities in colorectal cancer.
https://iris.unito.it/handle/2318/1715076

Corso, Simona, Isella, Claudio, Bellomo, Sara E, Apicella, Maria, Durando, Stefania, Migliore, Cristina, Ughetto, Stefano, D', Errico, Laura, Menegon, Silvia, Moya-Rull, Daniel, Cargnelutti, Marilisa, Capeloa, Tania, Conticelli, Daniela, Giordano, Jessica, Venesio, Tiziana, Balsamo, Antonella, Marchiò, Caterina, Degiuli, Maurizio, Reddavid, Rossella, Fumagalli Romario, Uberto, de Pascale, Stefano, Sgroi, Giovanni, Rausa, Emanuele, Baiocchi, Gian Luca, Molfino, Sarah, Pietrantonio, Filippo, Morano, Federica, Siena, Salvatore, Sartore-Bianchi, Andrea, Bencivenga, Maria, Mengardo, Valentina, Rosati, Riccardo, Marrelli, Daniele, Morgagni, Paolo, Rausei, Stefano, Pallabazzer, Giovanni, De Simone, Michele, Ribero, Dario, Marsoni, Silvia, Sottile, Antonino, Medico, Enzo, Cassoni, Paola, Sapino, Anna, Pectasides, Eirini, Thorner, Aaron R, Nag, Anwesha, Drinan, Samantha D, Wollison, Bruce M, Bass, Adam J, Giordano, Silvia (2019)
A comprehensive PDX gastric cancer collection captures cancer cell intrinsic transcriptional MSI traits.
https://iris.unito.it/handle/2318/1717860

Rospo G , Lorenzato A , Amirouchene-Angelozzi N , Magri A , Cancelliere C , Corti G , Negrino C , Amodio V , Montone M , Bartolini A , Barault L , Novara L , Isella C , Medico E , Bertotti A , Trusolino L , Germano G , Di Nicolantonio F , Bardelli A (2019)
Evolving neoantigen profiles in colorectal cancers with DNA repair defects.
https://iris.unito.it/handle/2318/1709286

Simona Corso, Marilisa Cargnelutti, Stefania Durando, Silvia Menegon, Maria Apicella, Cristina Migliore, Tania Capeloa, Stefano Ughetto, Claudio Isella, Enzo Medico, Andrea Bertotti, Francesco Sassi, Ivana Sarotto, Laura Casorzo, Alberto Pisacane, Monica Mangioni, Antonino Sottile, Maurizio Degiuli, Uberto Fumagalli, Giovanni Sgroi, Sarah Molfino, Giovanni De Manzoni, Riccardo Rosati, Michele De Simone, Daniele Marrelli, Luca Saragoni, Stefano Rausei, Giovanni Pallabazzer, Franco Roviello, Paola Cassoni, Anna Sapino, Adam Bass, Silvia Giordano (2018)
Rituximab Treatment Prevents Lymphoma Onset in Gastric Cancer Patient-Derived Xenografts.
https://iris.unito.it/handle/2318/1664042

Rangel, Nelson, Fortunati, Nicoletta, Osella-Abate, Simona, Annaratone, Laura, Isella, Claudio, Catalano, Maria Graziella, Rinella, Letizia, Metovic, Jasna, Boldorini, Renzo, Balmativola, Davide, Ferrando, Pietro, Marano, Francesca, Cassoni, Paola, Sapino, Anna, Castellano, Isabella* (2018)
FOXA1 and AR in invasive breast cancer: New findings on their co-expression and impact on prognosis in ER-positive patients.
https://iris.unito.it/handle/2318/1671592

Alderdice, Matthew, Richman, Susan D, Gollins, Simon, Stewart, James P, Hurt, Chris, Adams, Richard, McCorry, Amy MB, Roddy, Aideen C, Vimalachandran, Dale, Isella, Claudio, Medico, Enzo, Maughan, Tim, McArt, Darragh G, Lawler, Mark, Dunne, Philip D* (2018)
Prospective patient stratification into robust cancer-cell intrinsic subtypes from colorectal cancer biopsies.
https://iris.unito.it/handle/2318/1668949

Graudenzi, Alex, Maspero, Davide, Di Filippo, Marzia, Gnugnoli, Marco, Isella, Claudio, Mauri, Giancarlo, Medico, Enzo, Antoniotti, Marco, Damiani, Chiara (2018)
Integration of transcriptomic data and metabolic networks in cancer samples reveals highly significant prognostic power.
https://iris.unito.it/handle/2318/1691848

Vaira, M , Robella, M , Isella, C , Borsano, A , Mignone, A , Medico, E , De Simone, M (2018)
Transcriptional signature of Pseudomyxoma Peritonei: An enhancement of treatment strategy and outcome prediction.
https://iris.unito.it/handle/2318/1694958

D Avanzato, E Pupo, N Ducano, C Isella, G Bertalot, C Luise, S Pece, A Bruna, O M Rueda, C Caldas, P P Di Fiore, A Sapino, L Lanzetti (2018)
High USP6NL levels in breast cancer sustain chronic AKT phosphorylation and GLUT1 stability fueling aerobic glycolysis.
https://iris.unito.it/handle/2318/1670151

Luraghi, Paolo, Bigatto, Viola, Cipriano, Elia, Reato, Gigliola, Orzan, Francesca, Sassi, Francesco, De Bacco, Francesca, Isella, Claudio, Bellomo, Sara Erika, Medico, Enzo, Comoglio, Paolo M, Bertotti, Andrea, Trusolino, Livio, Boccaccio, Carla (2018)
A molecularly annotated model of patient-derived colon cancer stem-like cells to assess genetic and non-genetic mechanisms of resistance to anti-EGFR therapy.
https://iris.unito.it/handle/2318/1662775

Apicella M, Giannone E, Fiore S, Ferrari Kj, Fernandez-Perez D, Isella C, Granchi C, Minutolo F, Sottile A, Comoglio PM, Medico E, Pietrantonio F, Volante M, Pasini D, Chiarugi P, Giordano S, Corso S (2018)
Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies.
https://iris.unito.it/handle/2318/1691738

Rizzolio, Sabrina, Cagnoni, Gabriella, Battistini, Chiara, Bonelli, Stefano, Isella, Claudio, Van Ginderachter, Jo A , Bernards, René, Di Nicolantonio, Federica, Giordano, Silvia, Tamagnone, Luca (2018)
Neuropilin-1 upregulation elicits adaptive resistance to oncogene-targeted therapies.
https://iris.unito.it/handle/2318/1680726

Picco, Gabriele, Petti, Consalvo, Sassi, Francesco, Grillone, Katia, Migliardi, Giorgia, Rossi, Teresa, Isella, Claudio, Di Nicolantonio, Federica, Sarotto, Ivana, Sapino, Anna, Bardelli, Alberto, Trusolino, Livio, Bertotti, Andrea, Medico, Enzo (2017)
Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer.
https://iris.unito.it/handle/2318/1618636

Allegra, Sarah, Fatiguso, Giovanna, Calcagno, Andrea, Baietto, Lorena, Motta, Ilaria, Favata, Fabio, Cusato, Jessica, Bonora, Stefano, Di Perri, Giovanni, D', Avolio, Antonio (2017)
Role of vitamin D pathway gene polymorphisms on rifampicin plasma and intracellular pharmacokinetics.
https://iris.unito.it/handle/2318/1645884

Isella, Claudio, Brundu, Francesco, Bellomo, Sara E , Galimi, Francesco, Zanella, Eugenia, Porporato, Roberta, Petti, Consalvo, Fiori, Alessandro, Orzan, Francesca, Senetta, Rebecca, Boccaccio, Carla, Ficarra, Elisa, Marchionni, Luigi, Trusolino, Livio, Medico, Enzo, Bertotti, Andrea (2017)
Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer.
https://iris.unito.it/handle/2318/1642129

Ling, Hui, Pickard, Karen, Ivan, Cristina, Isella, Claudio, Ikuo, Mariko, Mitter, Richard, Spizzo, Riccardo, Bullock, Marc D , Braicu, Cornelia, Pileczki, Valentina, Vincent, Kimberly, Pichler, Martin, Stiegelbauer, Verena, Hoefler, Gerald, Almeida, Maria I , Hsiao, Annie, Zhang, Xinna, Primrose, John N , Packham, Graham K , Liu, Kevin, Bojja, Krishna, Gafà, Roberta, Xiao, Lianchun, Rossi, Simona, Song, Jian H , Vannini, Ivan, Fanini, Francesca, Kopetz, Scott, Zweidler-McKay, Patrick, Wang, Xuemei, Ionescu, Calin, Irimie, Alexandru, Fabbri, Muller, Lanza, Giovanni, Hamilton, Stanley R , Berindan-Neagoe, Ioana, Medico, Enzo, Mirnezami, Alex H , Calin, George A , Nicoloso, Milena S (2016)
The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis.
https://iris.unito.it/handle/2318/1615636

de Florian, D , Grojean, C , Maltoni, F , Mariotti, C , Nikitenko, A , Pieri, M , Savard, P , Schumacher, M , Tanaka, R , Aggleton, R , Ahmad, M , Allanach, B , Anastasiou, C , Astill, W , Badger, S , Badziak, M , Baglio, J , Bagnaschi, E , Ballestrero, A , Banfi, A , Barducci, D , Beckingham, M , Becot, C , Bélanger, G , Bellm, J , Belyaev, N , Bernlochner, F U , Beskidt, C , Biekötter, A , Bishara, F , Bizon, W , Bomark, N E , Bonvini, M , Borowka, S , Bortolotto, V , Boselli, S , Botella, F J , Boughezal, R , Branco, G C , Brehmer, J , Brenner, L , Bressler, S , Brivio, I , Broggio, A , Brun, H , Buchalla, G , Burgard, C D , Calandri, A , Caminada, L , Caminal Armadans, R , Campanario, F , Campbell, J , Caola, F , Carloni Calame, C M , Carrazza, S , Carvalho, A , Casolino, M , Cata, O , Celis, A , Cerutti, F , Chanon, N , Chen, M , Chen, X , Chokoufé Nejad, B , Christensen, N , Ciuchini, M , Contino, R , Corbett, T , Costa, R , Curtin, D , Dall', Osso, M , David, A , Dawson, S , de Blas, J , de Boer, W , de Castro Manzano, P , Degrande, C , Delgado, R L , Demartin, F , Denner, A , Di Micco, B , Di Nardo, R , Dittmaier, S , Dobado, A , Dorigo, T , Dreyer, F A , Dührssen, M , Duhr, C , Dulat, F , Ecker, K , Ellis, K , Ellwanger, U , Englert, C , Espriu, D , Falkowski, A , Fayard, L , Feger, R , Ferrera, G , Ferroglia, A , Fidanza, N , Figy, T , Flechl, M , Fontes, D , Forte, S , Francavilla, P , Franco, E , Frederix, R , Freitas, A , Freitas, F F , Frensch, F , Frixione, S , Fuks, B , Furlan, E , Gadatsch, S , Gao, J , Gao, Y , Garzelli, M V , Gehrmann, T , Gerosa, R , Ghezzi, M , Ghosh, D , Gieseke, S , Gillberg, D , Giudice, G F , Glover, E W N , Goertz, F , Gonçalves, D , Gonzalez-Fraile, J , Gorbahn, M , Gori, S , Gottardo, C A , Gouzevitch, M , Govoni, P , Gray, D , Grazzini, M , Greiner, N , Greljo, A , Grigo, J , Gritsan, A V , Gröber, R , Guindon, S , Haber, H E , Han, C , Han, T , Harlander, R , Harrendorf, M A , Hartanto, H B , Hays, C , Heinemeyer, S , Heinrich, G , Herrero, M , Herzog, F , Hespel, B , Hirschi, V , Hoeche, S , Honeywell, S , Huber, S J , Hugonie, C , Huston, J , Ilnicka, A , Isidori, G , Jäger, B , Jaquier, M , Jones, S P , Juste, A , Kallweit, S , Kaluza, A , Kardos, A , Karlberg, A , Z , Kassabov, Kauer, N , Kazakov, D I , Kerner, M , Kilian, W , Kling, F , Köneke, K , Kogler, R , Konoplich, R , Kortner, S , Kraml, S , Krause, C , Krauss, F , Krawczyk, M , Kulesza, A , Kuttimalai, S , Lane, R , Lazopoulos, A , Lee, G , Lenzi, P , Lewis, I M , Li, Y , Liebler, S , Lindert, J , Liu, X , Liu, Z , Llanes-Estrada, F J , Logan, H E , Lopez-Val, D , Low, I , Luisoni, G , Maierhöfer, P , Maina, E , Mansoulié, B , Mantler, H , Mantoani, M , Marini, A C , Martinez Outschoorn, V I , Marzani, S , Marzocca, D , Massironi, A , Mawatari, K , Mazzitelli, J , Mccarn, A , Mellado, B , Melnikov, K , Menari, S B , Merlo, L , Meyer, C , Milenovic, P , Mimasu, K , Mishima, S , Mistlberger, B , Moch, S - O , Mohammadi, A , Monni, P F , Montagna, G , Moreno Llácer, M , Moretti, N , Moretti, S , Motyka, L , Mück, A , Mühlleitner, M , Munir, S , Musella, P , Nadolsky, P , Napoletano, D , Nebot, M , Neu, C , Neubert, M , Nevzorov, R , Nicrosini, O , Nielsen, J , Nikolopoulos, K , No, J M , O', Brien, C , Ohl, T , Oleari, C , Orimoto, T , Pagani, D , Pandini, C E , Papaefstathiou, A , Papanastasiou, A S , Passarino, G , Pecjak, B D , Pelliccioni, M , Perez, G , Perrozzi, L , Petriello, F , Petrucciani, G , Pianori, E , Piccinini, F , Pierini, M , Pilkington, A , Plätzer, S , Plehn, T , Podskubka, R , Potter, C T , Pozzorini, S , Prokofiev, K , Pukhov, A , Puljak, I , Queitsch-Maitland, M , Quevillon, J , Rathlev, D , Rauch, M , Re, E , Rebelo, M N , Rebuzzi, D , Reina, L , Reuschle, C , Reuter, J , Riembau, M , Riva, F , Rizzi, A , Robens, T , Röntsch, R , Rojo, J , Romão, J C , Rompotis, N , Roskes, J , Roth, R , Salam, G P , Salerno, R , Sampaio, M O P , Santos, R , Sanz, V , Sanz-Cillero, J J , Sargsyan, H , Sarica, U , Schichtel, P , Schlenk, J , Schmidt, T , Schmitt, C , Schönherr, M , Schubert, U , Schulze, M , Sekula, S , Sekulla, M , Shabalina, E , Shao, H S , Shelton, J , Shepherd-Themistocleous, C H , Shim, S Y , Siegert, F , Signer, A , Silva, J P , Silvestrini, L , Sjodahl, M , Slavich, P , Slawinska, M , Soffi, L , Spannowsky, M , Speckner, C , Sperka, D M , Spira, M , Stål, O , Staub, F , Stebel, T , Stefaniak, T , Steinhauser, M , Stewart, I W , Strassler, M J , Streicher, J , Strom, D M , Su, S , Sun, X , Tackmann, F J , Tackmann, K , Teixeira, A M , Teixeira de Lima, R , Theeuwes, V , Thorne, R , Tommasini, D , Torrielli, P , Tosi, M , Tramontano, F , Trócsányi, Z , Trott, M , Tsinikos, I , Ubiali, M , Vanlaer, P , Verkerke, W , A , Vicini, Viliani, L , Vryonidou, E , Wackeroth, D , Wagner, C E M , Wang, J , Wayand, S , Weiglein, G , Weiss, C , Wiesemann, M , Williams, C , Winter, J , Winterbottom, D , Wolf, R , Xiao, M , Yang, L L , Yohay, R , Yuen, S P Y , Zanderighi, G , Zaro, M , Zeppenfeld, D , Ziegler, R , Zirke, T , Zupan, J (2016)
Handbook of LHC Higgs Cross Sections: 4. Deciphering the Nature of the Higgs Sector.
https://iris.unito.it/handle/2318/1657697

Bigatto, V, De Bacco, F, Casanova, E, Reato, G, Lanzetti, L, Isella, C, Sarotto, I, Comoglio, Pm, Boccaccio, C (2015)
TNF-α promotes invasive growth through the MET signaling pathway.
https://iris.unito.it/handle/2318/1506654

Petti C, Picco G, Martelli ML, Trisolini E, Bucci E, Perera T, Isella C, Medico E (2015)
Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells.
https://iris.unito.it/handle/2318/1508545

Isella, C, Terrasi, A, Bellomo, Se, Petti, C, Galatola, G, Muratore, A, Mellano, A, Senetta, R, Cassenti, A, Sonetto, C, Inghirami, G, Trusolino, L, Fekete, Z, De Ridder, M, Cassoni, P, Storme, G, Bertotti, A, Medico, E (2015)
Stromal contribution to the colorectal cancer transcriptome.
https://iris.unito.it/handle/2318/1508368

Cantini, Laura, Isella, Claudio, Petti, Consalvo, Picco, Gabriele, Chiola, Simone, Ficarra, Elisa, Caselle, Michele, Medico, Enzo (2015)
MicroRNA–mRNA interactions underlying colorectal cancer molecular subtypes.
https://iris.unito.it/handle/2318/1529830

Medico, E, Russo, M, Picco, G, Cancelliere, C, Valtorta, E, Corti, G, Buscarino, M, Isella, C, Lamba, S, Martinoglio, B, Veronese, S, Siena, S, Sartore-Bianchi, A, Beccuti, M, Mottolese, M, Linnebacher, M, Cordero, F, Di Nicolantonio, F*, Bardelli, A*, (*co-last and *corresponding authors) (2015)
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
https://iris.unito.it/handle/2318/1509370

Zanella ER, Galimi F, Sassi F, Migliardi G, Cottino F, Leto SM, Lupo B, Erriquez J, Isella C, Comoglio PM, Medico E, Tejpar S, Budinsk E, Trusolino L*, Bertotti A*(*Co-Senior e Corresponding Authors) (2015)
IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies.
https://iris.unito.it/handle/2318/1508351

L D′Amico, S Patanè, C Grange, B Bussolati, C Isella, L Fontani, L Godio, M Cilli, P D′Amelio, G Isaia, E Medico, R Ferracini, I Roato (2013)
Primary breast cancer stem-like cells metastasise to bone, switch phenotype and acquire a bone tropism signature.
https://iris.unito.it/handle/2318/140454

Isella C, Mellano A, Galimi F, Petti C, Capussotti L, De Simone M, Bertotti A, Medico E, Muratore A (2013)
MACC1 mRNA levels predict cancer recurrence after resection of colorectal cancer liver metastases.
https://iris.unito.it/handle/2318/143044

Migliore C, Martin V, Leoni VP, Restivo A, Atzori L, Petrelli A, Isella C, Zorcolo L, Sarotto I, Casula G, Comoglio PM, Columbano A, Giordano S (2012)
MiR-1 Downregulation Cooperates with MACC1 in Promoting MET Overexpression in Human Colon Cancer.
https://iris.unito.it/handle/2318/111437

Ferrero GB, Picco G, Baldassarre G, Flex E, Isella C, Cantarella D, Corà D, , , Chiesa N, Crescenzio N, Timeus F, Merla G, Mazzanti L, Zampino G, Rossi C, Silengo M, Tartaglia M, Medico E (2012)
Transcriptional hallmarks of noonan syndrome and noonan-like syndrome with loose anagen hair.
https://iris.unito.it/handle/2318/101486

Tessitore A , Capranica L , Messina R , Di Giuseppe F , Lupo C , Condello G (2012)
Analysis of linear sprints performed with a different arrival task in young soccer players.
https://iris.unito.it/handle/2318/145829

Sessa R, Seano G, di Blasio L, Gagliardi PA, Isella C, Medico E, Cotelli F, Bussolino F, Primo L (2012)
The miR-126 regulates Angiopoietin-1 signaling and vessel maturation by targeting p85β.
https://iris.unito.it/handle/2318/117561

Annaratone L, Marchiò C, Renzulli T, Castellano I, Cantarella D, Isella C, Macrì L, Mariscotti G, Balmativola D, Cantanna E, Deambrogio C, Pietribiasi F, Arisio R, Schmitt F, Medico E, Sapino A (2012)
High-throughput molecular analysis from leftover of fine needle aspiration cytology of mammographically detected breast cancer.
https://iris.unito.it/handle/2318/114398

Isella C, Renzulli T, Corà D, Medico E (2011)
Mulcom: a multiple comparison statistical test for microarray data in Bioconductor.
https://iris.unito.it/handle/2318/94343

Bertotti A, Migliardi G, Galimi F, Sassi F, Torti D, Isella C, Corà D, Di Nicolantonio F, Buscarino M, Petti C, Ribero D, Russolillo N, Muratore A, Massucco P, Pisacane A, Molinaro L, Valtorta E, Sartore-Bianchi A, Risio M, Capussotti L, Gambacorta M, Siena S, Medico E, Sapino A, Marsoni S, Comoglio PM, Bardelli A†, Trusolino L† (†Co-Senior authors) (2011)
A molecularly annotated platform of patient-derived xenografts (‘xenopatients’) identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer.
https://iris.unito.it/handle/2318/96346

Francesco Galimi, Davide Torti, Francesco Sassi, Claudio Isella, Davide Corà, Stefania Gastaldi, Dario Ribero, Andrea Muratore, Paolo Massucco, Dimitrios Siatis, Gianluca Paraluppi, Federica Gonella, Francesca Maione, Alberto Pisacane, Ezio David, Bruno Torchio, Mauro Risio, Mauro Salizzoni, Lorenzo Capussotti, Tim Perera, Enzo Medico, M F Di Renzo, Paolo M Comoglio, Livio Trusolino*, Andrea Bertotti* (*Co-Senior Authors) (2011)
Genetic and expression analysis of MET, MACC1 and HGF in metastatic colorectal cancer: Response to Met inhibition in patient xenografts and pathological correlations.
https://iris.unito.it/handle/2318/110677

Picco G, Cantarella D, Baldassarre G, Marinosci A, Dotta A, Isella C, Crescenzo N, Timeus F, Chiesa N, Merla G, Mazzanti L, Rossi C, Zampino G, Tartaglia M, Silengo M, Medico E, Ferrero GB (2010)
Analisi del profilo di trascrizione genetica nella sindrome di Noonan.
https://iris.unito.it/handle/2318/82248

A Mira, C Isella, T Renzulli, D Cantarella, M L Martelli, E Medico (2009)
The GAB2 signaling scaffold promotes anchorage independence and drives a transcriptional response associated with metastatic progression of breast cancer.
https://iris.unito.it/handle/2318/77339

S Tardito, C Isella, E Medico, L Marchiò, E Bevilacqua, M Hatzoglou, O Bussolati, R Franchi-Gazzola (2009)
The thioxotriazole copper(II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells.
https://iris.unito.it/handle/2318/74040

T Joyce, D Cantarella, C Isella, E Medico, A Pintzas (2009)
A molecular signature for Epithelial to Mesenchymal transition in a human colon cancer cell system is revealed by large-scale microarray analysis.
https://iris.unito.it/handle/2318/77761

Ferrero GB, Cantarella D, Baldassarre G, Isella C, Crescenzio N, Pagliano S, Silengo M, Medico E (2009)
Transcriptional hallmarks of Noonan syndrome in peripheral blood mononuclear cells.
https://iris.unito.it/handle/2318/71387

Ferrero GB, Cantarella D, Baldassarre G, Isella C, Crescenzo N, Timeus F, Chiesa N, Merla G, Mazzanti L, Rossi C, Zampino G, Tartaglia M, Silengo M, Medico E (2009)
Molecular dissection of Noonan syndrome by transcriptiome analysis.
https://iris.unito.it/handle/2318/69748

Perroni F, Tessitore A, Lupo C, D’Artibale E, Cortis C, Cignitti L, Capranica L (2008)
Energy Cost and Energy Sources During Simulated Fire-fighting Activity.
https://iris.unito.it/handle/2318/145787

Martelli ML, Isella C, Mira A, Fu L, Cantarella D, Medico E (2008)
Exploiting orthologue diversity for systematic detection of gain-of-functionphenotypes.
https://iris.unito.it/handle/2318/49723

Cortis C, Tessitore A, Lupo C, Capranica L (2008)
Inter-limb Coordination Performances Following a Young Basketball Match.
https://iris.unito.it/handle/2318/145796

ARENA S, ISELLA C, MARTINI M, DE MARCO A, MEDICO E, BARDELLI A (2007)
Knock-in of oncogenic Kras does not transform mouse somatic cells but triggers a transcriptional response that classifies human cancers.
https://iris.unito.it/handle/2318/36325

Courses

• ISTOLOGIA (INT0652)
  Corso di Laurea in Biotecnologie
• Multi-omics and Data Science for Precision Medicine (ONC0260)
  Artificial Intelligence for Biomedicine and Healthcare
• ONC0260A Genomics, transcriptomics, and phenotypic screenings (ONC0260A)
  Artificial Intelligence for Biomedicine and Healthcare
• Statistical Inference and Machine Learning
  PhD in Complex Systems for Quantitative Biomedicine

Activities in agenda

See my calendar

Academic bodies

• Department Council - Department of Oncology

• Consiglio di Dipartimento - Dipartimento di Oncologia