MRC Postdoctoral Research Scientist - London

MRC Postdoctoral Research Scientist - London

• Description: The Chromatin & Development group, led by Dr Michelle Percharde, investigates mechanisms of chromatin regulation in early mammalian development. We also study how chromatin regulation and other mechanisms are important for transposable element (TE) expression and function.

  In this project, the candidate will investigate the importance of nuclear structure and organization during mammalian development. Focusing on specific key proteins of interest in the lab, they will use a combination of mouse models and mouse embryonic stem cells (ESCs) to investigate the importance of nuclear and nucleolar organization in gene and chromatin regulation during embryonic development. The project will involve techniques routinely employed in the lab including imaging, genome-wide chromatin and transcriptomic analysis, molecular embryology and CRISPR/Cas9 manipulation.

  The post-holder will be a key member of the Chromatin & Development group, and as such will enjoy a high level of scientific responsibility. The successful candidate will have a strong background in development, chromatin, or gene regulation, with this post ideally suiting someone with experience working with mouse models or ESCs looking to delve further into chromatin and developmental biology.

• Location: London (UK)
• Website: here