The main aim of our lab is to decipher the rules underlying RNA structure formation and to dissect the role of the individual players (RBPs, PTMs, etc.), by means of NGS-based and computational approaches, in order to tackle the complexity of the in vivoRNA structurome.
We are interested in:
▪ Understanding the mechanistic aspects of RNA folding ▪ Investigating the crosstalk between RNA structure, PTMs and RBPs ▪ Characterizing the biological function of key RNA structure elements